IDH1 mutations are closely associated with CpG islet methylator pheno- group across tumor grade, raising the theorem that muta- tion may predispose cells to large-scale epigenetic disruption (Gupta and Salunke 2012; Noushmehr et al. 2010). In increment, the half-life of the Schiff bases is generally 2.5 hours (hemoglobin in serum second to…[Read more]